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In mammals, the vagina is the elastic, muscular part of the female genital tract extending, The vagina, including the vaginal opening, may be altered as a result of surgeries such as an episiotomy, vaginectomy, vaginoplasty or labiaplasty. Jan 18, Most women that I know learned how to look at their vaginas with hand mirrors somewhere around middle school. Either you heard about it in. Methods: Periurethral swabs and urine specimens were obtained from a total of girls (58 with vulvovaginitis and 43 without vulvovaginitis). Specimens were.
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älteres Frauengeschlecht a personalized all-access pass to everything local on events, music, restaurants, news and more. Most women that I know learned how look at their vaginas with hand mirrors somewhere around middle school.
Either you heard about it in health class, or your savvy friend told you, or you figured it out on your own whilst bored in your room älteres Frauengeschlecht day. But we were looking älteres Frauengeschlecht in the day just kind of What was älteres Frauengeschlecht on down there? What did things look like? Was there any reason to be concerned from a health perspective?
Well, like so much in our ever-changing world, all that is now different. Women are peeping their vag's with a critical eye, and many who don't like what they see are opting for a surgery called labiaplasty, in which the inner labia are reduced so älteres Frauengeschlecht they don't protrude from the outer labia.
This surgery isn't älteres Frauengeschlecht news; it's been around for
älteres Frauengeschlecht. But now, it's being enhanced; a doctor in Manhattan is doing what he calls "The Barbie" -- taking part of the outer labia in addition to the inner to emulate plastic Barbie doll with a flat vagina, and create what he calls a "comfortable, athletic, petite look.
You have successfully signed up for your selected newsletter s - please keep an eye on your mailbox, we're movin' in! Over at Guernicabold writer Kirsten O'Regan is going through the motions to find out what getting this labiaplasty entails.
There's the doctor, who insists that she's doing the right thing, the exuberant office assistant, the skeptic:. If you don't know those nuances, you're going to have dog-ears, or complete removal of the labia when that's not what's requested. That's when the lawsuits occur. All told, O'Regan paints a picture of a procedure that one can only hope won't take off in the mainstream:.
Some women undergo labiaplasty for medical or practical reasons--large labia can cause irritation and pain during sex and exercise--but the vast majority elect to undergo the surgery for cosmetic purposes, anxious to achieve a more attractive genital area. The desired "look" is consistently that of a smaller, less obtruding vulva, with "neat," even labia, and this "streamlined" ideal is becoming increasingly minimalist.
Or sign in with a social account: Ogilvie January 18, 3: If you like this story, consider signing up for our email newsletters. All-access pass to the top stories, events and offers around town. No Thanks Sign Up.
Shy girls?? pls help!The persistence of müllerian cells altered at the subcellular level could form the basis for development of carcinoma in later life. However, a similar sequence of. Jan 18, Most women that I know learned how to look at their vaginas with hand mirrors somewhere around middle school. Either you heard about it in..
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Estrogen regulation of tissue homeostasis, particularly the regulation of cell proliferation and differentiation in female reproductive organs, is interesting both in its basic biology and in several disease models and cancer biology. Using an epithelial estrogen receptor 1 Esr1 conditional knockout mouse model, we showed that vaginal epithelial cells lacking ESR1 failed to activate growth factor signaling and remained undifferentiated and in a proliferative state throughout the epithelium.
Thus, epithelial ESR1 mediates the switch between cell proliferation and squamous cell differentiation, demonstrating unique roles of ESR1 in the female reproductive tract. Estrogen-mediated actions in female reproductive organs are tightly regulated, mainly through estrogen receptor 1 ESR1. The mouse vaginal epithelium cyclically exhibits cell proliferation and differentiation in response to estrogen and provides a unique model for analyzing the homeostasis of stratified squamous epithelia.
To address the role of ESR1-mediated tissue events during homeostasis, we analyzed mice with a vaginal epithelium-specific knockout of Esr1 driven by keratin 5-Cre K5-Esr1KO. We show here that loss of epithelial ESR1 in the vagina resulted in aberrant epithelial cell proliferation in the suprabasal cell layers and led to failure of keratinized differentiation.
Gene expression analysis showed that several known estrogen target genes, including erbB growth factor ligands, were not induced by estrogen in the K5-Esr1KO mouse vagina.
Organ culture experiments revealed that the addition of erbB growth factor ligands, such as amphiregulin, could activate keratinized differentiation in the absence of epithelial ESR1. Thus, epithelial ESR1 integrates estrogen and growth factor signaling to mediate regulation of cell proliferation in squamous differentiation, and our results provide new insights into estrogen-mediated homeostasis in female reproductive organs.
Estrogens play important roles in vertebrate reproductive biology, with effects principally mediated through the nuclear estrogen receptors ESRs.
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Epithelial estrogen receptor 1 intrinsically mediates squamous differentiation in the mouse vagina
At what time one first thinks of a vagina, one simply thinks of it as being a aisle for conception, birth, and menstruation. It is the site of deposition of a male's sperm for the purpose of fertilizing a female's egg.
When a fetus finally completes gestation, before growth and development inside the mother, the baby must go through the vagina to access a new world. When a female reaches reproductive age moreover starts to ovulate, an unfertilized egg will be disposed of and sloughed out through the vagina. All of this information seems sufficient to fully be familiar with the vagina.
However, the vagina is not as simple equally one may think. Different conditions in a female's life possibly will give rise to different green changes inside the vagina. Also during these environmental changes, a number of microbes, innate and foreign, induce the ability to be distorted.
In mammals , the vagina is the elastic, muscular part of the female genital tract extending, in humans, from the vulva to the cervix. The outer vaginal opening is normally partly covered by a membrane called the hymen.
At the deep end, the cervix neck of the uterus bulges into the vagina. The vagina allows for sexual intercourse and childbirth , and channels menstrual flow menses , which occurs as part of the monthly menstrual cycle. The vagina's location and structure varies among species, and can vary in size. Female mammals usually have two external openings in the vulva, the urethral opening for the urinary tract and the vaginal opening for the genital tract.
This is different from male mammals, who usually have a single urethral opening for both urination and reproduction. The vaginal opening is much larger than the nearby urethral opening, and both are protected by the labia in humans. In amphibians , birds , reptiles and monotremes , the cloaca is the single external opening for the gastrointestinal tract, the urinary, and reproductive tracts.
In some women, the symptoms of altered vaginal flora are recognized as bacterial vaginosis (BV); in others the change is silent or subclinical but nonetheless. Apr 1, especially in the face of the rising popularity of labiaplasty, a cosmetic surgery in which the labia minora and labia majora are altered. The persistence of müllerian cells altered at the subcellular level could form the basis for development of carcinoma in later life. However, a similar sequence of.